Laparoscopic Adjustable Gastric Banding for the Treatment of Grade 3 Obesity, Metabolic Complications
LAGB Induces Improves Weight, Arterial Blood Pressure, Body Fat Distribution, Glucose and Lipid Metabolism
| Bariatric Surgery information Laparoscopic Adjustable Gastric Banding for the Treatment of Grade 3 Obesity, Metabolic Complications |
LAGB Induces Improves Weight, Arterial Blood Pressure, Body Fat Distribution, Glucose and Lipid Metabolism |
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Weight Loss Surgery Information - Bariatric Research Studies |
Laparoscopic Adjustable Gastric Banding for the Treatment of Grade 3 Obesity and Its Metabolic Complications: A Three Year StudyWeight loss ameliorates arterial hypertension and glucose metabolism in obese patients, but the dietary approach is unsatisfactory because obesity relapses. Durable reduction of body weight, obtained through major nonreversible surgical procedures, such as jejunal and gastric bypass, allows improvement of glucose metabolism and arterial blood pressure in morbid (grade 3) obesity. Laparoscopic adjustable gastric banding (LAGB) is a minimally invasive and reversible surgical procedure that yields a significant reduction of gastric volume and hunger sensation. In this study, 143 patients with grade 3 obesity [27 men and 116 women; age, 42.9 +/- 0.83 yr; body mass index (BMI), 44.9 +/- 0.53 kg/m(2); normal glucose tolerance; impaired glucose tolerance; type 2 diabetes mellitus underwent Laparoscopic adjustable gastric banding and a 3-year follow-up for clinical (BMI, waist circumference, waist to hip ratio, and arterial blood pressure) and metabolic variables (glycosylated hemoglobin, fasting insulin and glucose, insulin and glucose response to oral glucose tolerance test, homeostasis model assessment index, total and high-density lipoprotein cholesterol, triglycerides, uric acid, and transaminases). Method At baseline and 1 year after Laparoscopic adjustable gastric banding, patients underwent computerized tomography and ultrasound evaluation of visceral and sc adipose tissue. One-year metabolic results were compared with 120 obese patients receiving standard dietary treatment. Results Laparoscopic adjustable gastric banding induced a significant and persistent
weight loss and decrease of blood pressure. Greater metabolic effects
were observed in T2DM patients than in NGT and IGT patients, so that at
3 yr glycosylated hemoglobin was no longer different in NGT and T2DM subjects.
Clinical and metabolic improvements were proportional to the amount of
weight loss. Conclusion We conclude that Laparoscopic adjustable gastric banding is an effective treatment of grade 3 obesity in inducing long-lasting reduction of body weight and arterial blood pressure, modifying body fat distribution, and improving glucose and lipid metabolism, especially in T2DM. Source: Bariatric Weight Loss Surgery |