Laparoscopic Adjustable Gastric Banding - Treatment of Grade 3 Obesity
Stomach Banding to Treat
Morbid obesity
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Stomach Banding to Treat |
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Laparoscopic Adjustable Gastric Banding for the Treatment of Morbid
(Grade 3) Obesity and its Weight reduction ameliorates arterial hypertension and glucose metabolism in obese patients, but the dietary approach is unsatisfactory because obesity relapses. Durable reduction of body weight, obtained through major non-reversible surgical procedures, such as jejunal and gastric bypass, allows improvement of glucose metabolism and arterial blood pressure in morbid (grade 3) obesity. Laparoscopic adjustable gastric banding (LAGB) is a minimally invasive and reversible surgical procedure that yields a significant reduction of gastric volume and hunger sensation. Study Method In this study, 143 patients with grade 3 obesity underwent laparoscopic adjustable gastric banding and a 3-year follow-up for clinical (BMI, waist circumference, waist to hip ratio, and arterial blood pressure) and metabolic variables (glycosylated hemoglobin, fasting insulin and glucose, insulin and glucose response to oral glucose tolerance test, homeostasis model assessment index, total and high-density lipoprotein cholesterol, triglycerides, uric acid, and transaminases). At baseline and 1 yr after Laparoscopic adjustable gastric banding, patients underwent computerized tomography and ultrasound evaluation of visceral and sc adipose tissue. One-year metabolic results were compared with 120 obese patients receiving standard dietary treatment. Study Results Laparoscopic adjustable gastric banding induced a significant and persistent weight loss and decrease of blood pressure. Greater metabolic effects were observed in T2DM patients than in NGT and IGT patients, so that at 3 year glycosylated hemoglobin was no longer different in NGT and T2DM subjects. Clinical and metabolic improvements were proportional to the amount of weight loss. Laparoscopic adjustable gastric banding induced a greater reduction of visceral fat than sc fat. At 1-year evaluation, weight loss and metabolic improvements were greater in Laparoscopic adjustable gastric banding-treated than diet-treated patients. Study Conclusions We conclude that LAGB is an effective treatment of grade 3 obesity in inducing long-lasting reduction of body weight and arterial blood pressure, modifying body fat distribution, and improving glucose and lipid metabolism, especially in T2DM. Source: Stomach Bypass Surgery Information |