Ghrelin Levels After Laparoscopic Bypass and Silicone Gastric Banding
What Happens to Plasma Ghrelin After Bypass or Stomach Band
| Bariatric Surgery information Ghrelin Levels After Laparoscopic Bypass and Silicone Gastric Banding |
What Happens to Plasma Ghrelin After Bypass or Stomach Band |
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Weight Loss Surgery To Reduce Obesity - Research Into Gastric Reduction Surgery |
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Different Plasma Ghrelin Levels after Laparoscopic Gastric Bypass
and Adjustable Gastric Banding in Gastric bypass has been reported to be associated with markedly suppressed plasma ghrelin levels, suggesting that it is one of the possible weight-reducing factors related to this procedure. The aim of this study was the evaluation of plasma ghrelin levels in patients who had undergone laparoscopic Roux-en-Y gastric bypass (LRYGBP) and laparoscopic adjustable silicone gastric banding (LASGB). Method Normal weight, obese subjects and patients who had undergone total gastrectomy were used as controls. In this cross-sectional study, we selected 10 subjects who underwent LASGB, 11 subjects with laparoscopic Roux-en-Y gastric bypass, 10 obese subjects, eight patients with total gastrectomy, and eight normal weight subjects. Plasma ghrelin, insulin, and glucose profiles were determined before and after breakfast and lunch. Results Obese subjects showed a ghrelin plasma level significantly lower than normal weight subjects. Patients with laparoscopic Roux-en-Y gastric bypass showed baseline ghrelin levels lower than laparoscopic adjustable silicone gastric banding. Both groups of patients who underwent bariatric surgical procedures also had ghrelin lower than normal weight and obese subjects. Patients with total gastrectomy showed plasmatic ghrelin levels extremely lower than those in all other groups. The ghrelin profile in both groups of subjects who underwent laparoscopic Roux-en-Y gastric bypass and laparoscopic adjustable silicone gastric banding did not show any meal-related changes as observed in obese and normoweight control groups. Significant difference in plasma ghrelin levels between LRYGBP and laparoscopic adjustable silicone gastric banding was found, suggesting that both procedures could induce weight loss by different mechanisms in which ghrelin could be involved. Authors: Source: Stomach Bypass Surgery Information |